SEPRAFILM

Adhesions are not preventable by surgical technique alone.  Adhesions develop routinely following surgery, and have been reported at second-look surgery to occur in up to 93% of patients (n=210) following laparotomy2. SEPRAFILM Adhesion Barrier is an adhesion barrier that reduces the incidence, extent and severity of adhesions following abdominopelvic surgery1,2.
Seprafilm membrane held with forceps

Adhesions are not preventable by surgical technique alone

Adhesions develop routinely following both open and laparoscopic abdominal surgery, and have been reported at second-look surgery to occur in up to 93% of patients (n=210) following laparotomy2.

Seprafilm Adhesions Graph

SEPRAFILM efficacy in abdominal surgery

In a randomised, prospective, double-blinded, multicenter clinical study involving 183 patients [175 evaluable] with ulcerative colitis and familiar polyposis undergoing 2-stage intestinal resection, more than half of the patients treated with SEPRAFILM were adhesion-free at 12 weeks compared to 6% of untreated patients2.

Graph showing 35% adhesion rate reduction in Seprafilm users

SEPRAFILM efficacy in pelvic surgery

In a prospective, randomised, blinded, multicenter clinical study involving 127 patients undergoing gynecologic surgery, SEPRAFILM reduced the mean number of sites adherent to the anterior uterine surface following myomectomy compared with untreated patients. SEPRAFILM also significantly reduced the extent and severity of adhesions in patients undergoing uterine myomectomy compared with untreated patients3.

Additional Product Benefits

Protection When It Matters Most

Separates tissues for up to 7 days - the critical tissue healing period1,2

A Proven Legacy

More than 4 million patients have received SEPRAFILM in clinical use worldwide. Robust clinical data (n=2,133) across five clinical studies have demonstrated the safety and efficacy of SEPRAFILM Adhesion Barrier. 2-6

Bioresorbable and Synthetic

SEPRAFILM is composed of sodium hyaluronate and carboxymethylcellulose (HA/CMC)